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PSILO: A repository for protein-ligand structural information

Web-based Search

  • Flexible and intuitive user interface
  • Fast and powerful Google™-like search
  • BLAST searches, small molecule similarity and protein family searching
  • Track favorite searches, hit lists, email notifications
  • PSILO integration into browser search bar
  • Download structures as PDB, mmCIF or XML
  • Superimpose related protein sites to compare binding modes


Version Control

  • Easy to import data
  • Deposit new structures/edit existing structures to create new versions
  • Track and maintain structure versions
  • Graphical comparisons of structure files
  • Increase quality of structures with commenting


Central Data Repository

  • Automatic annotation with PFAM, GO and geometric checks
  • Straightforward deposit (bulk deposit via command language)
  • Easily linked to proprietary sequence and/or ligand databases
  • Automatic updates of the Protein Data Bank (PDB)
  • Download search results (MOL, image format, XML, PDB)


Standard Web Infrastructure

  • Works with Oracle®and MySQL®
  • HTTP-based Application Programming Interface (API)
  • Source code provided
  • Simple to maintain and deploy
  • Customizable - to work with non-standard PDB files

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