Notice

The computer software identified by the name "MOE", and/or other similar names, the computer software identified by the name "SVL", and/or other similar names, the related computer programs, documentation, data files and all copies of the foregoing in any form (together "MOE") is the exclusive property of Chemical Computing Group ULC ("CCG"), or its licensors, and is protected by Canadian, United States, European and/or international copyright and/or intellectual property laws.

MOE is CONFIDENTIAL INFORMATION and may not be used, accessed or disclosed except in accordance with a Software License Agreement ("SLA") between users and CCG or an authorized distributor of CCG. The (possibly temporary) availability of MOE or components of MOE on any computer network shall not be construed as publication, nor shall such availability impair the confidential nature of or components of MOE.

The contents of the MOE documentation are confidential and protected by Canadian, United States, and international copyright laws. All files available in the documentation provided by CCG may be viewed, printed, and used for information purposes only, provided that the files remain intact with all copyright notices clearly visible.

THIS DOCUMENTATION IS PROVIDED "AS IS" WITHOUT WARRANTY OF ANY KIND. IN NO EVENT SHALL CCG OR ITS LICENSORS BE LIABLE FOR ANY LOSS OF PROFITS, LOSS OF BUSINESS, LOSS OF USE OR DATA, INTERRUPTION OF BUSINESS, OR FOR INDIRECT, SPECIAL, INCIDENTAL, OR CONSEQUENTIAL DAMAGES OF ANY KIND, ARISING FROM ANY ERROR IN THIS DOCUMENTATION.

MOE, SVL, and the Chemical Computing Group ULC logo are trademarks of CCG or its licensors. IBM and DB2 are trademarks or registered trademarks of International Business Machines Corporation. Silicon Graphics is a registered trademark of Silicon Graphics, Inc. Java and SUN are registered trademarks of Oracle and/or its affiliates. UNIX is a registered trademark in the United States and other countries licensed exclusively through X/Open Company Ltd. Windows is a trademark of Microsoft Corporation. Apple and Macintosh are registered trademarks of Apple Computer, Inc. Sigma-Aldrich is the registered trademark of Merck KGaA. Intel is a registered trademark of Intel Corporation. Other product or brand names are trademarks or registered trademarks of their respective holders. CCG indemnifies, defends, and holds harmless Microsoft from any claims, including attorneys' fees, related to the distribution or use of CCG's programs.

The MOE distribution contains the following software, listed with their copyright and licensing information. Additional details can be found in the summaries of third party commercial, noncommercial, and web app noncommercial versions and licenses.

OpenMOPAC. Copyright © J.J.P. Stewart, Stewart Computational Chemistry. CCG makes no copyright, confidentiality, or other intellectual property rights claim regarding the OpenMOPAC program, which has been placed by its authors into the public domain under the terms of the GNU Lesser General Public License (LGPL), Version 3. OpenMOPAC. OpenMOPAC. OpenMOPAC program.

GZIP. The Free Software Foundation claims ownership of the GZIP program under the GNU General Public License, Version 2, 1991. gzip. gzip. gzip program.

Flexera Software Tools. The lmgrd, lmtools, lmutil and chemcompd programs are provided under license from Flexera Software. CCG has limited its activities in relation to the Flexera software to providing license management for CCG products on various computer platforms.

Busybox. The busybox program is provided under the GNU General Public License, Version 2, 1991. CCG distributes a version of busybox compiled from source code obtained from https://github.com/rmyorston/busybox-w32.git using a configuration file that is available upon a request. busybox. busybox. busybox program.

MKL. Selected portions of the Intel oneAPI redistributable Mathematical Kernel Library provided under license from Intel Corporation. Copyright © 2002–2022 Intel Corporation. All rights reserved. CCG has limited its activities in relation to the MKL software to providing dynamic libraries containing portions of the MKL libraries for various computer platforms. MKL.

Intel Compiler OpenMP library. Copyright Intel Corporation, 2022. The Intel oneAPI redistributable OpenMP library is distributed under license from Intel Corporation. Intel Compiler OpenMP.

Microsoft Visual Studio C++ Utilities and Run Time Libraries. Copyright Microsoft Corporation, 2022. The msvcrt, msvcr110, msvcp110, mscvrt140, mscvp140, and vcruntime140 libraries are distributed under license from Microsoft Corporation. mscvrt140, mscvp140, and vcruntime140.

FFTW. Copyright © 2003, 2007–8 Matteo Frigo, Copyright © 2003, 2007–8 Massachusetts Institute of Technology. The libfftw3 library is provided under license from the Massachusetts Institute of Technology. FFTW. FFTW.

Zlib. Copyright © 1995–2004 Jean-loup Gailly and Mark Adler. Permission has been granted to use this software for any purpose, including commercial applications, according to the zlib licensing notice. zlib. zlib.

Infernal. Copyright © 1991–2020 Sean R. Eddy, with additional copyright information provided in the Infernal license notice. Infernal includes the HMMER software package (license and copyright information below). The Infernal programs are distributed under the BSD (Berkeley Software Distribution) open source license. Infernal. CCG modified version 1.1.4 of the Infernal programs for the purpose of compiling them on various computer platforms using shared libraries. The MOE distribution includes the cmbuild, cmconvert, cmpress, cmscan, and cmsearch programs and the libinfernal and libinfernalimpl libraries. Infernal.

HMMER. Copyright © 1992–2020 Sean R. Eddy, with additional copyright information provided in the HMMER license notice. The HMMER programs are distributed under the terms of the BSD (Berkeley Software Distribution) open source license. The HMMER software uses the Easel software library version 0.48, Copyright © 1990–2020 Sean R. Eddy, with additional copyright information provided in the Easel license notice. The Easel software library is distributed under the terms of the BSD (Berkeley Software Distribution) open source license. The HMMER software uses the libdivsufsort library, Copyright © 2003–2008 Yuta Mori, All rights reserved, which is available to be redistributed and/or modified under the terms of the MIT License. HMMER. CCG modified version 3.3.2 of the HMMER programs for the purpose of compiling them on various computer platforms using shared libraries. The MOE distribution includes the hmmbuild, hmmconvert, hmmpress, hmmscan, and hmmsearch programs and the libhmmer and libhmmerimpl libraries. HMMER.

cURL. Copyright © 1996–2024 Daniel Stenberg. All rights reserved. Permission to use, copy, modify, and distribute this software for any purpose with or without fee has been granted under the cURL copyright notice. cURL.

SSL. OpenSSL, Copyright © 1998–2019 The OpenSSL Project. All rights reserved. This product includes software developed by the OpenSSL Project for use in the OpenSSL Toolkit (http://www.openssl.org/). The OpenSSL toolkit stays under a dual license, i.e. both the conditions of the OpenSSL License and the original SSLeay license apply to the toolkit. This product includes cryptographic software written by Eric Young (eay@cryptsoft.com). This product includes software written by Tim Hudson (tjh@cryptsoft.com). Original SSLeay license: Copyright © 1995–1998 Eric Young. OpenSSL.

Kerberos. Copyright © 1985–2018 Massachusetts Institute of Technology. All rights reserved. Downloading of this software may constitute an export of cryptographic software from the United States of America that is subject to the United States Export Administration Regulations (EAR), 15 CFR 730-774. Additional laws or regulations may apply. It is the responsibility of the person or entity contemplating export to comply with all applicable export laws and regulations, including obtaining any required license from the U.S. government. See the copyright notice for further details. Kerberos is licensed in accordance with the MIT Kerberos Copyright information. Individual source code files are copyright MIT, Cygnus Support, Novell, OpenVision Technologies, Oracle, Red Hat, Sun Microsystems, FundsXpress, and others, as detailed in the MIT Kerberos License information page. Kerberos.

SQLite. SQLite has been dedicated to the public domain by its authors, who have disclaimed copyright. SQLite.

RISM. A. Kovalenko, T. Luchko and D.A. Case claim ownership of the 3D-RISM-KH program under the GNU General Public License, Version 3. 3D-RISM-KH. rism3d. rism3d program.

Cairo. libcairo is free software available to be redistributed and/or modified under the terms of either the GNU Lesser General Public License (LGPL), Version 2.1 or the Mozilla Public License (MPL), Version 1.1. cairo. cairo. libcairo library.

Pixman. libpixman is free and open source software with multiple attributions. It is available to be redistributed and/or modified under the terms of the MIT License. pixman. pixman.

Iconv. The libiconv library is provided by the Free Software Foundation under the GNU Lesser General Public License (LGPL), Version 2. iconv. iconv. libiconv library.

JPEG. libjpeg is based in part on the work of the Independent JPEG Group. The Independent JPEG Group claims ownership of JPEG software (libjpeg), Copyright © 1991–2012 Thomas G. Lane, Guido Vollbeding. All Rights Reserved except as specified in the JPEG licensing notice. JPEG. JPEG.

jQuery. jQuery Foundation Projects, Copyright © 2005–2015 The jQuery Foundation (now the OpenJS Foundation). The OpenJS Foundation jQuery Project, including the jQuery Core library, the jQuery UI library, the jQuery Mobile framework, and the jQuery Migrate plugin, are released under the terms of the MIT License. Copyright and licensing details of components used in MOE are provided in this notice, including additional individual OpenJS Foundation jQuery Project components, distributed in accordance with their respective MIT and New BSD licenses. OpenJS Foundation jQuery Project.

Vue. Copyright © 2018-present, Yuxi (Evan) You. The Vue framework is released under the terms of the MIT License. Copyright and licensing details of components used in MOE are provided in this notice, including additional individual Vue components, distributed in accordance with their MIT licenses. Vue.

Ubuntu Fonts. Licensed under the Ubuntu Font Licence v1.0. Ubuntu FONT.

Torsion Analyzer. The Torsion Analyzer software in MOE uses the Torsion Library jointly developed by the University of Hamburg, Center for Bioinformatics, Hamburg, Germany and F. Hoffmann-La-Roche Ltd., Basel, Switzerland, as described in J. Med. Chem. 56 (2013) 2016–2028, J. Chem. Inf. Model 56 (2016) 1–5, and J. Chem. Inf. Model 62 (2022) 1644–1653. The torsion library is available in the supplementary information to J. Med. Chem. 56 (2013) 2016–2028.

MSDN Example Code. Code is included that has been derived from example code from MSDN, copyright Microsoft Corporation, and which is included under the terms of the Microsoft Public License. All rights reserved.

Base64.java. Derived from Base64.java from The Android Open Source Project, Copyright © 2010. Licensed under the Apache License, Version 2.0 ("Apache–2.0"). See Apache–2.0 for the specific language governing permissions and limitations under Apache–2.0. Software distributed under Apache–2.0 is distributed on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. Base64.java.

libstdc++. Copyright © 1994-2002 Free Software Foundation. The Standard C++ library is licensed under the GNU Lesser General Public License (LGPL), Version 3, with additional permissions granted under the GCC Runtime Library Exception, Version 3.1. libsdtc++. libsdtc++ library.

libpthread. The POSIX Threading Library is provided by the Free Software Foundation under the GNU Lesser General Public License (LGPL), Version 2.1.