SUPPORT AND TRAINING

Upcoming Educational Events

Workshops & Webinars

PM 
Structure-Based Drug Design
PM 
PRESENTATION:
Computational Approaches for Optimizing the Developability of Biotherapeutics
PM 
WORKSHOPS:
  
Modeling Antibody-Antigen Complexes
  
Analyzing Antibody-Antigen Complexes
  
Structural Bioinformatics
  
Property Prediction and Protein Engineering
AM 
Antibody Modeling and Protein Engineering in MOE
PM 
Biologics: Protein Alignments, Modeling and Docking
AM 
Structure-Based Drug Design and Ligand Modification
PM 
Small Molecule Virtual Screening
New and Enhanced Features in MOE 2019.01
See all European Workshops
See all North American Workshops
See all Webinars

Meetings

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UGM & Conference 2019, North America

June 25-28, 2019Montreal, Canada

Our annual scientific meeting is a 4-day event consisting of 2 days of workshops and 2 days of scientific presentations, as well as plenty of opportunities to socialize during our receptions and a conference dinner.

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UGM & Conference 2019, Europe

May 21-24, 2019Oxford, UK

Our annual scientific meeting is a 4-day event consisting of 2 days of workshops and 2 days of scientific presentations, as well as plenty of opportunities to socialize during our receptions and a conference dinner.

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Courses and Tutorials

Courses

Structure-Based Drug Design and Ligand Modification

 MOE 2018   molecular surfaces and maps - ligand interactions - conformational searching - ligand optimization - ligand selectivity - protein alignments and superposition


Advanced Structure-Based Design

 MOE 2018   pharmacophore modeling - docking - fragment-based design - scaffold replacement - R-group screening - project search - protein-ligand interaction fingerprints (PLIF)


Antibody Modeling and Protein Engineering in MOE

 MOE 2018   protein engineering - protein properties - developability - hot spot analysis - antibody modeling - humanization - molecular surfaces


Biologics: Protein Alignments, Modeling and Docking

 MOE 2018   alignments and superposition - loop and linker modeling - homology modeling - protein docking - solubility analysis - 2D hot spot mapping - protein ligand interaction fingerprints - QSAR modeling


Ligand-Based Drug Design and SAR Analysis

 MOE 2018   R-group profiles and analysis - MOEsaic - mmp analysis - descriptor calculations - conformational searching - molecular alignments - pharmacophore modeling and searching - diversity analysis


Cheminformatics and QSAR

 MOE 2018   MOE databases - calculated descriptors - fingerprints - QSAR modeling - binary QSAR - similarity searching - consensus modeling


Introduction to SVL

 MOE 2018   SVL - programming language - create scripts - customize MOE


MOE Project and Protein Family Modeling

 MOE 2018   MOE project - database management - specialized protein families - project data search - PLIF analysis


PSILO

 PSILO 2017   macromolecular repository - display electron density - 3D query searching - pocket similarity - central repository - specialized protein databases


Peptide Modeling, Conformational Searching and Docking

 MOE 2018   structure preparation - non-natural amino acids - conformational searching - distance restraints - peptide-protein docking - protein-ligand interaction fingerprints


Protein Alignments and Homology Modeling

 MOE 2018   homology modeling - loop modeling - loop conformational searching - sequence alignments - structure superposition - multimer alignments and superpositions


Small Molecule Virtual Screening

 MOE 2018   virtual screening compound libraries - descriptor, property and activity filtering - pharmacophores - docking - compound design


X-Ray Crystallography and Solvent Analysis

 MOE 2018   structure preparation - sidechain rotamer exploration - electron density maps - solvent analysis with 3D-RISM


Tutorials

Docking

 MOE 2018   protonate 3D - ligand docking - pharmacophore query - ligand pose analysis - surfaces and maps


Homology Modeling of Proteins

 MOE 2018   homologous sequence search - sequence alignments - protein templates - homology modeling - protein geometry - homology model evaluation


Protein Design

 MOE 2018   hot spot analysis - identify mutation sites - optimize protein properties - predict affinity and stability - calculate protein properties


Scaffold Replacement

 MOE 2018   fragment tools - scaffold replacement - pharmacophore model - ligand properties


Structure-Based Drug Design

 MOE 2018   SBDD - structure preparation - SiteView - QuickPrep - 2D ligand interactions - surfaces and maps - molecule builder


3D Visualization and Making Pictures

 MOE 2018   protein and ligand preparation - active site visualization - 2D ligand interactions diagrams - molecular surfaces - rendering options


Domain Motif Searching in MOE

 MOE 2018   structural search - sequence independent search - domain motif - similar stuctural motif - nuclear receptor family


Flexible Alignment

 MOE 2018   building polysaccharides - oligosaccharides - carbohydrates - anomeric center - structure minimization


LowModeMD

 MOE 2018   conformational search - loop sampling - tethered restraints - LowModeMD - shape descriptors


MedChem Transformations In-Cleft

 MOE 2018   molecular transformations - reactions - active site constraints - modification in the receptor pocket


Pharmacophore Query Editing and Searching

 MOE 2018   pharmacophores - extended hueckel theory - query editor - excluded volumes - pharmacophore search


Protein Alignment and Superposition

 MOE 2018   sequence alignments - structural superposition - sequence similarity - sequence identity


Protein Ligand Interaction Fingerprints (PLIF)

 MOE 2018   protein alignments - protein-ligand databases - PLIF - phamacophore query generator


QSAR: Modeling Experimental Data

 MOE 2018   QSAR - molecular descriptors - model validation - data analysis - plots


SD Pipelining Tools - How to Create a Fragment Database

 MOE 2018   SD pipeline tools - fragment database - scaffold replacement - data preparation - molecular conformations