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We are pleased to announce that the next CCG European UGM and Conference will take place May 30 to June 2 2023, in München / Munich, Germany. This is a 4-day event, consisting of workshops, scientific presentations, and a poster session as well as social activities including receptions and a conference dinner.

If you are interested in presenting at the meeting, please contact Steve Maginn at .

TUESDAY, May 30 - Workshops
DAY 1
12:00
Registration Open
13:30-16:30
Peptide Modeling, Conformational Searching and Docking 
Structure preparation / Non-natural amino acids / Conformational searching / Distance restraints / Peptide-protein docking / Protein-ligand interaction fingerprints
13:30-16:30
Fragment-Based Drug Design 
Scaffold Replacement / Medicinal Chemistry Transformations / Fragment Linking / R-Group Screening / Ligand Growing / Pharmacophores / Fragment Databases
WEDNESDAY, May 31 - Workshops & Poster Session
DAY 2
08:30-09:00
Welcome Refreshments
09:00-12:00
Advanced Structure-Based Design 
Pharmacophore Modeling / Docking / Fragment-based Design / Scaffold Replacement / R-Group Screening / Project Search / Protein-Ligand Interaction Fingerprints (PLIF)
09:00-12:00
Antibody Modeling and Protein Engineering 
Protein Engineering / Protein Properties / Developability / Hot Spot Analysis / Antibody Modeling / Humanization / Molecular Surfaces
12:00-13:00
Lunch Break
13:00-16:00
Small Molecule Virtual Screening 
Virtual Screening Compound Libraries / Descriptors, Fingerprints and QSPR Modeling / Pharmacophore Modeling / Template-based Docking / Compound Design
13:00-16:00
Biologics: Protein Alignments, Modeling and Docking 
Alignments and Superposition / Loop and Linker Modeling / Homology Modeling / Protein Docking / Solubility Analysis / 2D Hot Spot Mapping / Protein Ligand Interaction Fingerprints / QSAR Modeling
18:30-20:30
Opening Reception and Poster Session (Sofitel Hotel )
20:45-22:15
Optional Munich Walking Tour
THURSDAY, June 1 - Scientific Presentations
DAY 3
08:30-08:55
Welcome Refreshments
08:55-09:00
Opening Remarks
09:00-09:30
Computational Approaches for the Design and Development of Multispecific therapeutics 
Dilyana Dimova, Senior Data Scientist, Sanofi
09:30-10:00
Using Machine-learning to Reduce the Risks Associated with Biopharmaceutical Formulation Development 
Mark Teese, Product Owner, Bioinformatics, Leukocare AG
10:00-10:30
Modeling Conformational Dynamics of Antibodies - Consequences for Biophysical Properties 
Monica Fernández-Quintero, Postgraduate Research Scientist, Leopold-Franzens Universität Innsbruck
10:30-11:00
Morning Break
11:00-11:30
Design Adaptions for mRNA Encoded Antibodies 
Wolfgang Große, Associate Director, Protein Design, CureVac SE
11:30-12:00
Multiscale Biomolecular Simulations for Design of Lipid Nanoparticles for mRNA Vaccines 
Anastasia Markina, Scientist, Chem- & Bio-informatics, BioNTech SE
12:00-12:30
Extending the Design Toolbox with Multi-Modal Monte Carlo Tree Search 
James Webster, Senior Scientist, In Silico R&D, Evotec (UK) Ltd.
12:30-14:00
Lunch Break
14:00-14:30
Embedding Dynamics in Intrinsic Physicochemical Profiles of Market-Stage Antibody-Based Biotherapeutics 
Giuseppe Licari, Lead Scientist, Computational Structural Biology, Merck KGaA
14:30-15:00
From Static to Dynamic: Exploring Ensemble Protein Properties with Graph Neural Networks from Crystal Structures 
Maximilian Ebert, Director, Computational Molecular Sciences, and Michael-Rock Goldsmith, Co-founder & Chief Innovation Officer, Congruence Therapeutics
15:00-15:30
Reverse Fingerprinting: Application to Motif Detection and Pharmacophore Query Generation 
Andrew Henry, Principal Scientist, Chemical Computing Group
15:30-16:00
Afternoon Break
16:00-16:30
Proteolysis Targeting Molecules: Chimeras or Chameleons? 
Ekaterina Ratkova, Associate Principal AI Scientist, AstraZeneca Gothenburg
16:30-17:00
Modeling Ternary Complexes with Molecular Glues: Making Sense of a Sticky Situation 
Michael Drummond, Scientific Applications Manager, Chemical Computing Group
18:30-22:00
Reception and Conference Dinner (Bayerischer Hof Hotel )
FRIDAY, June 2 - Scientific Presentations
DAY 4
08:30-09:00
Welcome Refreshments
09:00-09:30
Goller
09:30-10:00
Beyond Halogen Bonding: The Next Generation of Fragments and Perspectives for Molecular Design 
Frank Böckler, Professor of Pharmaceutical Chemistry, Eberhard Karls Universität Tübingen
10:00-10:30
Binding Site Comparison - Current Pitfalls & Potential Solutions 
Peter Schmidtke, Scientific Project Manager, Discngine
10:30-11:00
Morning Break
11:00-11:30
Streamlining Virtual Screening for Faster Hit Identification 
Chetan Chintha, Scientist, Computational Chemistry, Nuvisan
11:30-12:00
Automating Workflows with KNIME 
Chimed Jansen, Associate Principal Scientist, Computational Chemistry, Acerta Pharma BV
12:00-12:30
A Toolkit for Fast Covalent Docking Developed by Combining GOLD, MOE, KNIME, and Python Programs 
Obdulia Rabal, Group Leader, Molecular Architect, Evotec SE, Toulouse
12:30-14:00
Lunch Break
14:00-14:30
How AI is REINVENTing Drug Discovery 
Graeme Robb, Director, Computational Chemistry, AstraZeneca Cambridge
14:30-15:00
Identification and Optimization of a Novel Class of KRASG12C Inhibitors, Leading to the Discovery of JDQ443 
Simona Cotesta, Director, Global Discovery Chemistry, Novartis
15:00-15:30
Selective Small Molecule Activation of PKG1α: Structure and Function 
Essam Metwally, Principal Scientist, Merck Research Labs
15:30-15:40
Closing Remarks
15:40-16:30
Closing Reception
There will be a poster session to be held on the evening of Wednesday 31st May as part of the Opening Reception, to take place at the nearby Sofitel Hotel Bayerpost.