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We are pleased to announce that the next CCG European UGM and Conference is returning to an "in-person" format and will take place on May 17-20 in Amsterdam, Netherlands. This is a 4-day event, consisting of workshops, scientific presentations, and a poster session as well as social activities including receptions and a conference dinner.

If you are interested in presenting at the meeting, please contact Steve Maginn at .

TUESDAY, May 17 - Workshops
DAY 1
12:00
Registration Open
13:00-16:00
Small Molecule Virtual Screening 
Virtual Screening Compound Libraries / Descriptors, Fingerprints and QSPR Modeling / Pharmacophore Modeling / Template-based Docking / Compound Design
13:00-16:00
Introduction to SVL 
SVL Concepts / Scripts for Moe/Batch / Test New Ideas/Hypotheses / Customize MOE / Programming Techniques / Window Toolkit / Descriptors and Fingerprints / Interactive Problem Solving
WEDNESDAY, May 18 - Workshops & Poster Session
DAY 2
09:00-12:00
Fragment-Based Drug Design 
Scaffold Replacement / Medicinal Chemistry Transformations / Fragment Linking / R-Group Screening / Ligand Growing / Pharmacophores / Fragment Databases
09:00-12:00
Antibody Modeling and Protein Engineering 
Protein Engineering / Protein Properties / Developability / Hot Spot Analysis / Antibody Modeling / Humanization / Molecular Surfaces
12:00-13:00
Lunch Break
13:00-16:00
Advanced Structure-Based Drug Design 
Pharmacophore Modeling / Docking / Fragment-based Design / Scaffold Replacement / R-Group Screening / Project Search / Protein-Ligand Interaction Fingerprints
13:00-16:00
Biologics: Protein Alignments, Modeling and Docking 
Protein Alignments and Superposition / Loop and Linker Modeling / Homology Modeling / Protein- Protein Docking
18:30-20:30
Opening Reception and Poster Session
20:45
Optional Amsterdam Walking Tour
THURSDAY, May 19 - Scientific Presentations
DAY 3
08:30-08:50
Welcome Refreshments
08:50-09:00
Opening Remarks
09:00-09:30
Protein Dynamics in Nuclear Hormone Receptors Impacting Design and Allosteric Cross-talk 
Anders Hogner, Director, Medicinal Chemistry, AstraZeneca
09:30-10:00
Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode 
Henriette Willems, Senior Research Associate, Computational Chemistry, ALBORADA Drug Discovery Institute
10:00-10:30
Morning Break
10:30-11:00
Exploiting Protein-Ligand Interaction Statistics for Structure-Based Drug Design 
Bernd Kuhn, Distinguished Scientist, Roche
11:00-11:30
Application of MOE in Collaborative Design in a Fragment Based Discovery Project 
Ann Vos, Senior Scientist, Computer Aided Drug Design, Janssen
11:30-12:00
Electrostatic Jaggedness – a Descriptor to Augment Efflux Models 
Steve St-Gallay, Principal Scientist, MSD
12:00-13:30
Lunch Break
13:30-14:00
The ReSCoSS Workflow: QM Conformer Landscapes and Property Predictions for MedChem Projects 
Rainer Wilcken, Senior Principal Scientist, Novartis
14:00-14:30
FMO-guided Identification of PPI Hotspots and Modulators 
Stefania Monteleone, Senior Scientist, Computational Chemistry, Evotec UK Ltd.
14:30-15:00
Database autoph4: Pharmacophore Analysis of Multiple Protein Structures 
Chris Williams, Director of Scientific Support, Principal Scientist, Chemical Computing Group
15:00-15:30
Afternoon Break
15:30-16:00
Molecular Glues to Stabilize 14-3-3 Protein-Protein Interactions
Christian Ottmann, Founder and CTO, Ambagon Therapeutics
16:00-16:30
Synthetic Macrocycles & Prediction of Permeability 
Anna Rzepiela, Computational Chemist, Pyxis Discovery B.V.
16:30-17:00
The Sociology and Psychology of Successful Design; Lessons Learned
Richard Lewis, Director, Data Science, Novartis
18:30
Reception and Conference Dinner at Bridges Restaurant, Sofitel Legend The Grand Amsterdam
FRIDAY, May 20 - Scientific Presentations
DAY 4
08:30-09:00
Welcome Refreshments
09:00-09:30
AI in Drug Discovery 2022 – Aspects of Translation, Validation, and Where We are on the Hype Cycle
Andreas Bender, CSO, Terra Lumina, and Professor of Molecular Informatics, University of Cambridge
09:30-10:00
In Silico vs In Vitro: Identification of Surface Epitopes in Proteins 
Joanna Czulak, Head of Molecular Modelling, MIP Diagnostics
10:00-10:30
Computational Profiling of Pharmacokinetics for Multi-specific Antibodies  
Pep Amengual-Rigo, Postdoctoral Data Scientist, Sanofi
10:30-11:00
Morning Break
11:00-11:30
Rapid Discovery of Potent and Selective GIP-R Binders through mRNA-display Coupled to Bioinformatics Analysis and Modelling 
Marina Kasimova, Senior Modelling Scientist, Novo Nordisk
11:30-12:00
Structure-Based Charge Calculations for Predicting Properties and Profiling Antibody Therapeutics 
Nels Thorsteinson, Director of Biologics, Chemical Computing Group
12:00-13:30
Lunch Break
13:30-14:00
IgG1 Conformational Behavior: Elucidation of the N-glycosylation Role via Molecular Dynamics 
Simona Saporiti, Research Assistant, Università degli studi di Milano (IT)
14:00-14:30
Enhancing Protein Degrader Discovery through Integration of Computational Chemistry 
Lewis Vidler, Principal Computational Chemist, Amphista Therapeutics
14:30-15:00
Developing Free Energy Techniques to Help Guide Pharmaceutical Lead Optimization 
David Mobley, Professor, Pharmaceutical Sciences and Chemistry, UC Irvine
15:00-15:15
Closing Remarks
15:15
Closing Reception

No further poster abstracts can be accepted.