We are excited to announce that the next CCG North American UGM & Conference will be held from June 23-26 in Montreal, Canada. This 4-day event will feature workshops, scientific presentations, a poster session, and social activities, including receptions and a conference dinner.
If you would be interested in presenting at the meeting, please contact Raul Alvarez at .
Perspectives on Current Approaches to Virtual Screening in Drug Discovery
Joerg Bentzien, Director, Computational Chemistry,Alkermes
Joerg Bentzien, Director, Computational Chemistry,
Structure-driven epitope/paratope analysis to advance biologics discovery, design, and optimization
Ryan Casner, Scientist,Sanofi
Ryan Casner, Scientist,
Structure-Based Vaccine Design Starts to Deliver
Ye Che, Senior Director,GSK
Ye Che, Senior Director,
Lead Identification of Novel Ion Channel Blockers for the Treatment of Rare Epilepsies
Carla-Maria Gauss, Editor,LiveCoMS
Carla-Maria Gauss, Editor,
Presentation Title to Be Announced
Lindsay Hammack, Associate Principal Scientist,Merck
Lindsay Hammack, Associate Principal Scientist,
Integration of QSAR Models with High Throughput Screening to Accelerate the Development of Polishing Chromatography Unit Operations
Michael Hartmann, Associate Principal Scientist,Merck
Michael Hartmann, Associate Principal Scientist,
Structure Guided Optimization of a Selective Molecular Glue Degrader for Oncology
David Kornfilt, Principal Scientist,Remix Therapeutics
David Kornfilt, Principal Scientist,
Enhanced Rational Protein Engineering to Reduce Viscosity in High-Concentration IgG1 Antibody Solutions
Tyler Lefevre, Senior Scientist,AstraZeneca
Tyler Lefevre, Senior Scientist,
Machine Learning Tools for mAbs Developability Predictions Utilizing MOE
Kozo Yoneda, Senior Scientist,Daiichi Sankyo, Inc.
Kozo Yoneda, Senior Scientist,
Presentation Title to be Announced
Speaker to be confirmed,X-Chem Inc.
Speaker to be confirmed,
Registration Opens (check-in/badge pick-up)
Welcome Refreshments
Topic: RNA Modeling (description to come)
Peptide Modeling, Conformational Searching and Docking
Structure preparation / Non-natural amino acids / Protein Design / Conformational searching / Distance restraints / Peptide-Protein docking / Protein-Ligand Interaction Fingerprints (PLIFs)
Structure preparation / Non-natural amino acids / Protein Design / Conformational searching / Distance restraints / Peptide-Protein docking / Protein-Ligand Interaction Fingerprints (PLIFs)
Ligand-based Drug Design and Interactive SAR and MMP Analysis
MOEsaic / Matched Molecular Pairs / R-group analysis / Similarity and substructure searching / Multi-parameter optimization / Free-Wilson analysis / Molecular alignments / Pharmacophores
MOEsaic / Matched Molecular Pairs / R-group analysis / Similarity and substructure searching / Multi-parameter optimization / Free-Wilson analysis / Molecular alignments / Pharmacophores
Lunch Break
Antibody Modeling and Protein Engineering
Protein Engineering / Protein Properties / Protein Contacts / Developability / Molecular surfaces / Hot spot analysis / Antibody modeling
Protein Engineering / Protein Properties / Protein Contacts / Developability / Molecular surfaces / Hot spot analysis / Antibody modeling
Cheminformatics: Manage, Analyze, Model and Mine Molecular Data
MOE databases / Molecular descriptors / Database filters / Sorting and coloring / Plots / Clustering / Diverse subset selection / QSAR modeling / Binary QSAR / Substructure searching / Molecular fingerprints / Similarity searching
MOE databases / Molecular descriptors / Database filters / Sorting and coloring / Plots / Clustering / Diverse subset selection / QSAR modeling / Binary QSAR / Substructure searching / Molecular fingerprints / Similarity searching
Welcome Refreshments
Biologics: Protein Alignments, Modeling and Docking
Alignments and superposition / Loop and linker modeling / Protein-Protein docking / Protein-Ligand Interaction Fingerprints (PLIFs) / Epitope analysis / Homology modeling / Solubility analysis / QSAR modeling / 2D hot spot mapping
Alignments and superposition / Loop and linker modeling / Protein-Protein docking / Protein-Ligand Interaction Fingerprints (PLIFs) / Epitope analysis / Homology modeling / Solubility analysis / QSAR modeling / 2D hot spot mapping
SBDD: Generating and Prioritizing Novel Design Ideas using Docking and Fragments-based Optimization
Protein-ligand interactions / Protein-ligand docking / Pharmacophore modeling / Template-based docking / Scaffold replacement / R-group exploration / Bioisosteric transformations / Ligand properties / PLIFs
Protein-ligand interactions / Protein-ligand docking / Pharmacophore modeling / Template-based docking / Scaffold replacement / R-group exploration / Bioisosteric transformations / Ligand properties / PLIFs
Organizing Structural Families: PSILO and MOE-Project
PSILO / Central macromolecular repository / 3D Query searching / Pocket similarity / Display electron density / MOE-project / Project search / Organizing and centralizing project data / Protein family modeling
PSILO / Central macromolecular repository / 3D Query searching / Pocket similarity / Display electron density / MOE-project / Project search / Organizing and centralizing project data / Protein family modeling
Lunch Break
Scientific Presentations
Opening Reception & Poster Session
Group Activities (Evening Brewery Visit or Historic Walking Tour)
Scientific Presentations
Lunch Break
Scientific Presentations
Drinks Reception and Conference Dinner
Scientific Presentations
Lunch Break
Desserts & Drinks Closing Reception
There will be a poster session on Wednesday, June 24. Prospective presenters are invited to submit their poster abstracts as part of the registration process. Submission deadline: Saturday, May 30.
We look forward very much to seeing you in Montreal this coming June!